Most patients undergoing ketamine therapy for Complex Regional Pain Syndrome (CRPS), formerly called Reflex Sympathetic Dystrophy (RSD), will require four to eight treatments on back-to-back days initially, followed by periodic "boosters" of one to two back-to-back treatments.  For most people, treatments last months to years.

On the day of treatment, patients will need either a trusted family member or friend to drive them home and stay with them.  All patients will have a history and physical exam performed.  An IV will be started.  During the infusion, patients are monitored continuously.  Most infusions last between four and six hours.